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Discrete element method software

Chromatography - Some Objectives of Using CAE

  • Understand effects of distributor and collector designs and process parameters on flow field.
  • Define a system that provides "plug flow".
  • Eliminate back mixing in distribution system

Some Benefits of Using CAE

  • Identify key physical design parameters to increase performance.
  • Identify process parameters that does not have a significant effect on system performance. (e.g., the equipment design was controlling a parameter).

Process Parameters

  • Flow rate
  • Inlet velocity
  • Screen permeability
  • Packed bed permeability
  • Distributor & collector geometry



Chromatography Calculations Using Passage Software

  • Velocity field inside column
  • Determine flow uniformity, plug flow
  • Locate channeling & vortexing regions
  • Back mixing in distributors
  • Statistical analysis of velocity variations
  •  Degree of velocity variation and percentage of column affected
  • Performance comparison of different column configurations

Passage®/ DEM+FLOW Software

Example: Fluidized Bed Granulation of Tablets
Flow Model - Air Velocity
DEM Model Particles
Example: Mixing of Powders
DEM Model
FLOW Model
Example: Printing of Toners- Development Process (sample pictures)
Toner Voltage
Print pattern
Passge DEM Toner Voltage

Passage Discerete Element Modeling (DEM) Print Pattern


Passage Licensing Options:

Technalysis offers various licensing options and support to fit your needs and budget. Contact us to discuss your needs. E-mail or call 317-291-1985

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